While randomized-controlled trials (RCTs) have spotlighted ketamine's acute efficacy, questions persist about its real-world applicability.

They analyzed the records of patients who received these infusions in Veterans Health Administration hospitals

A systematic review and meta-analysis indicated that IV ketamine is nearly three times more effective than intranasal esketamine

Summary of evaluating and alternative treatments of treatment-resistant depression

Ketamine represents a new treatment option, and randomised trials show a rapid effect of intravenous ketamine.

Dr Maria Dobreva calls on medical schemes to support comprehensively the “Holy Grail of antidepressant treatments”

Given the complexity of the diagnosis, any additional tool – such as ketamine – in the therapeutic arsenal is helpful.

Short-term clinical trials found intravenous (IV) ketamine to be effective in reducing depressive symptoms.

For answers to all the questions you may be having about ketamine, we turned to Steven L. Mandel, M.D., a board-certified anesthesiologist