While randomized-controlled trials (RCTs) have spotlighted ketamine's acute efficacy, questions persist about its real-world applicability.

They analyzed the records of patients who received these infusions in Veterans Health Administration hospitals

The effects of IV DMT on mental health outcomes, particularly focusing on its potential in comparison to psilocybin

Recent clinical trials have shown that psychedelics, especially psilocybin, can be effective in alleviating symptoms of depression

while psilocybin shows promise for treating depression, substantial concerns regarding safety, and regulatory issues must be addressed

Summary of evaluating and alternative treatments of treatment-resistant depression

Ketamine represents a new treatment option, and randomised trials show a rapid effect of intravenous ketamine.

Dr Maria Dobreva calls on medical schemes to support comprehensively the “Holy Grail of antidepressant treatments”

Given the complexity of the diagnosis, any additional tool – such as ketamine – in the therapeutic arsenal is helpful.